Relapsing polychrondritis is an inflammatory disorder that affects cartilage in the ear, nose, larynx, and tracheobronchial tree. This intermittent, yet sometimes progressive disorder can also be associated with ocular manifestations, aortic regurgitation, and premonitory asymmetric oligoarthritis affecting some large and small peripheral joints. Diagnosis of relapsing polychrondritis can be made in the presence of the aforementioned clinical features; biopsy of affected tissues displaying cartilage destruction would be confirmatory, but is usually unnecessary. Patients with Wegener’s granulomatosis may have nasal, but not auricular involvement.  Cogan’s syndrome may include ocular and auditory problems, but does not involve the external ear. There was not urethritis or skin lesions inb this case to suggest Reiter’s syndrome. The arthritis in rheumatoid disease tends to be symmetric and erosive. Squamous cell carcinoma would be unlikely to involve both ears and the larynx simultaaneously.